Tissue fluidity promotes epithelial wound healing
نویسندگان
چکیده
منابع مشابه
JBP485 promotes corneal epithelial wound healing
Proper wound healing is vital for maintenance of corneal integrity and transparency. Corneal epithelial damage is one of the most frequently observed ocular disorders. Because clinical options are limited, further novel treatments are needed to improve clinical outcomes for this type of disease. In the present study, it was found that placental extract-derived dipeptide (JBP485) significantly i...
متن کاملThrombomodulin Promotes Corneal Epithelial Wound Healing
PURPOSE To determine the role of thrombomodulin (TM) in corneal epithelial wound healing, and to investigate whether recombinant TM epidermal growth factor-like domain plus serine/threonine-rich domain (rTMD23) has therapeutic potential in corneal epithelial wound healing. METHODS TM localization and expression in the murine cornea were examined by immunofluorescence staining. TM expression a...
متن کاملNotch inhibition during corneal epithelial wound healing promotes migration.
PURPOSE To determine the role of Notch signaling in corneal epithelial migration and wound healing. METHODS Immunolocalization of Notch1 was performed during epithelial wound healing in vivo in mouse corneal epithelial debridement wounds and in vitro in primary human corneal epithelial cells following a linear scratch wound. The effects of Notch inhibition, using the γ-secretase inhibitor N-(...
متن کاملCorneal epithelial wound healing.
The corneal surface is, without question, the most specialised 123 mm2* of the body's surface. It forms an integral part of the ocular surface with which it shares several anatomical and physiological attributes. Like the rest ofthe body surface, it is in a state of constant 'healing'. Squamous epithelial cells are continually shed into the tear pool and simultaneously replenished by cells movi...
متن کاملConjunctival epithelial wound healing.
In vivo conjunctival epithelial healing in albino rabbits was investigated by light microscopy following both n-heptanol and trephined conjunctival wounding. Reepithelialization occurred faster following n-heptanol treatment (3 days) versus trephination (6-7 days). No goblet cells were present in the migrating epithelium during reepithelialization. After 1 day of wounding, goblet cells disappea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Physics
سال: 2019
ISSN: 1745-2473,1745-2481
DOI: 10.1038/s41567-019-0618-1